Projected demographic composition of the United States population of people living with diagnosed HIV
The transformation of HIV from a fatal disease to lifelong disease has resulted in an HIV-infected population that is growing and aging, placing new and increasing demands on public programs and health services. We used National HIV Surveillance System and US census data to project the demographic composition of the population of people living with diagnosed HIV (PLWDH) in the United States through 2045.
A cross-sectional analysis of Trichomonas vaginalis infection among heterosexual HIV-1 serodiscordant African couples
Trichomonas vaginalis is the most prevalent curable STI worldwide and has been associated with adverse health outcomes and increased HIV-1 transmission risk. We conducted a cross-sectional analysis among couples to assess how characteristics of both individuals in sexual partnerships are associated with the prevalence of male and female T. vaginalis infection.
Association of recent bacterial vaginosis with acquisition of Mycoplasma genitalium
This study assessed the association between recent bacterial vaginosis (BV) and incident Mycoplasma genitalium, a sexually transmitted bacterium associated with adverse female reproductive health outcomes.
This is your new normal: A qualitative study of barriers and facilitators to physical activity in Veterans with lower extremity loss
Regular physical activity (PA) is essential for aging well with a disability, preventing the onset or worsening of chronic conditions, functional loss, and maintaining or improving quality of life, yet PA levels are low in those with disabilities, including those with a lower extremity amputation (LEA).
Mild cognitive impairment in Parkinson's disease versus Alzheimer's disease
This study provides further evidence that Parkinson's disease (PD-MCI) is clinically distinct from Alzheimer's Disease (AD-MCI) and requires different tools for diagnosis and monitoring clinical progression. More importantly, this study suggests that PD-MCI takes longer to convert into dementia than AD-MCI, findings that require replication by other studies.
A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts
The Nurses’ Health Study (NHS), Nurses’ Health Study II (NHSII), Health Professionals Follow Up Study (HPFS) and the Physicians Health Study (PHS) have collected detailed longitudinal data on multiple exposures and traits for approximately 310,000 study participants over the last 35 years. To allow for secondary analyses of these data, this study created three new datasets merged by platform family and performed imputation using a common reference panel, the 1,000 Genomes Phase I release.
Replacing American snacks with tree nuts increases consumption of key nutrients among US children and adults: results of an NHANES modeling study
Replacing typical American snacks with tree nuts may be an effective way to improve diet quality and compliance with the 2015-2020 Dietary Guidelines for Americans (DGAs).
Operationalizing the Measurement of Seroadaptive Behaviors: A Comparison of Reported Sexual Behaviors and Purposely-Adopted Behaviors Among Men who have Sex with Men (MSM) in Seattle
Dietary biomarker evaluation in a controlled feeding study in women from the Women's Health Initiative cohort
The objectives were 1) to simultaneously associate dietary intake with a range of potential nutritional biomarkers in postmenopausal women by using a controlled feeding study whereby each participant was provided a diet similar to her usual diet and 2) to evaluate serum concentrations of select nutrients as potential biomarkers with the use of established urinary recovery biomarkers of energy and protein as benchmarks for evaluation.
Reproductive factors and risk of colorectal polyps in a colonoscopy-based study in western Washington State
Oral contraceptives (OC) are associated with a decreased risk of colorectal cancers; however, a recent study reported an increased risk of small colorectal adenomas associated with OC use. Our results suggest that reproductive factors, including OC use, are not associated with early colorectal cancer precursor lesions.