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Brief report: anal intercourse, HIV-1 risk, and efficacy in a trial of a dapivirine vaginal ring for HIV-1 prevention

Journal of Acquired Immune Deficiency Syndromes, Sunday, March 1, 2020

The objective of this study was to describe receptive anal intercourse (RAI) behaviors and correlates in a cohort of sub-Saharan African women, evaluate the association of RAI with HIV-1 risk, and evaluate whether the HIV-1 prevention efficacy of a dapivirine vaginal ring differs among women who reported RAI.

High prevalence of vaginal and rectal mycoplasma genitalium macrolide resistance among female STD clinic patients in Seattle, Washington

Sexually Transmitted Diseases, Tuesday, February 18, 2020

Rectal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) are increasingly recognized as common infections among women. Little is known about the prevalence of rectal Mycoplasma genitalium (MG) , rectal MG/CT/GC co-infection, or MG antimicrobial resistance patterns among women.

Analysing the affordability of the EAT-Lancet diet

The Lancet Global Health, Wednesday, January 8, 2020

The need to produce planet-friendly foods that are both affordable and nutrient-rich presents a challenge to agricultural food systems.

Usability and feasibility of an innovative mLearning approach for nurses providing option B+ services in Manica and Sofala provinces, Mozambique.

The Journal of the Association of Nurses in AIDS Care, Wednesday, January 1, 2020

The scaling of Option B+ services, whereby all pregnant women who test HIV positive are started on lifelong antiretroviral therapy upon diagnosis regardless of CD4 T-cell count, is ongoing in many high HIV burden, low-resource countries.

Catechol-O-Methyltransferase and Cardiovascular Disease: MESA.

Journal of the American Heart Association, Monday, December 16, 2019

Genetic variation in catechol-O-methyltransferase (COMT), a key enzyme in estrogen and catecholamine metabolism, has plausible physiological links to cardiovascular disease (CVD) and its risk factors.

Association of long-term ambient ozone exposure with respiratory morbidity in smokers

JAMA Internal Medicine, Monday, December 9, 2019

The objective of this study was to investigate the association of historical ozone exposure with risk of chronic obstructive pulmonary disease (COPD), computed tomography (CT) scan measures of respiratory disease, patient-reported outcomes, disease severity, and exacerbations in smokers with or at risk for COPD.

Longitudinal investigation of military-specific factors associated With continued unhealthy alcohol use among a large US military cohort

Journal of Addiction Medicine, Monday, December 9, 2019

The objective of this study was to examine whether military separation (Veteran), service component (active duty, Reserve/National Guard), and combat deployment are prospectively associated with continuing unhealthy alcohol use among US military service members.

Association of CD14 with incident dementia and markers of brain aging and injury

Neurology, Monday, December 9, 2019

This study's objective was to test the hypothesis that the inflammatory marker plasma soluble CD14 (sCD14) associates with incident dementia and related endophenotypes in 2 community-based cohorts.

Magnetic resonance imaging brain atrophy assessment in primary age-related tauopathy (PART)

Acta Neuropathologica Communications, Monday, December 9, 2019

Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the accumulation of amyloid-beta (Aβ) plaques and tau neurofibrillary tangles (NFTs). Recently, primary age-related tauopathy (PART) has been described as a new anatomopathological disorder where NFTs are the main feature in the absence of neuritic plaques. However, since PART has mainly been studied in post-mortem patient brains, not much is known about the clinical or neuroimaging characteristics of PART.

Sex differences in the association between pentraxin 3 and cognitive decline: the cardiovascular health study

The Journals of Gerontology, Friday, December 6, 2019

The importance of systemic inflammation, measured by C-reactive protein, in cognitive decline has been demonstrated; however, the role of vascular inflammation is less understood. Pentraxin 3 (PTX3) is a novel marker of vascular inflammation.