School of Public Health

Lindstroem, Sara

Sara Lindstroem

Assistant Professor, Epidemiology

Education

MSc Engineering Physics, Umea University, 2004
PhD Genetic Epidemiology, Umea University, 2007

Contact Info

University of Washington
Office F247B
Box 357236
Department of Epidemiology
Health Sciences Building
Tel: 206-221-3148
saralind@uw.edu

Links

Get to Know Dr. Sara Lindstroem: Genetic Epidemiologist

Research Interests

My research focuses on understanding the genetic contribution to common complex diseases, with a primary emphasis on cancer and linked traits. By leveraging long-running large population-based studies, I investigate how our genetics and environment affect our risk of developing disease.

Current research projects include studying the shared genetic origin between common cancers and the genetics underlying childhood obesity, breast tissue composition and venous thromboembolism. I am also interested in finding approaches to incorporate information about the functional characteristics of the genome in my studies. Finally, I am involved in several large-scale international collaborations that study the genetics underlying breast and prostate cancer.

Publications

Michailidou K, Beesley J, Lindström S, (other authors), Chenevix-Trnech G, Hall P, Easton DF. Combined GWAS analysis of more than 120,000 individuals identifies 15 novel susceptibility loci for breast cancer. Nat Genet. 2015 Apr;47(4):373-80.

Lindström S, Thompson DJ, Paterson AD, (other authors), Boyd NF, Vachon CM, Tamimi RM. Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. Nature Commun. 2014 Oct 24;5:5303.

Cao Y, Lindström S, Schumacher F, (other authors), Pollak M, Lin X, Ma J. Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival. J Natl Cancer Inst. 2014 May 13;106(6)

Garcia-Closas M*, Couch, FJ*, Lindström S*, Michailidou K*, Schmidt MK*, (other authors), Pharoah P, Vachon C, Easton DF, Haiman CA, Kraft P. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet. 2013 Apr;45(4):392-8. *These authors contributed equally to this work.

Campa D, Kaaks R, Le Marchand L, (other authors), Hunter DJ, Lindström S, Canzian F. Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. J Natl Cancer Inst. 2011 Aug 17;103(16):1252-63.

Lindström S, Vachon CM, Li J, (other authors), Easton DF, Boyd NF, Tamimi RM. Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. Nat Genet.2011 Mar;43(3):185-7.

Lindström S, Adami HO, Balter KA, Xu J, Zheng SL, Sun J, Stattin P, Gronberg H, Wiklund F. Inherited genetic variation in hormone regulating genes and prostate cancer survival. Clin Cancer Res. 2007 Sep 1;13(17):5156-6

Lindström S, Wiklund F, Adami HO, Balter KA, Adolfsson J, Gronberg H. Germ-Line Genetic Variation in the Key Androgen-Regulating Genes Androgen Receptor, Cytochrome P450, and Steroid-5-{alpha}-Reductase Type 2 Is Important for Prostate Cancer Development. Cancer Res. 2006 Nov 15;66(22):11077-83 Dec;118(3-4):339-47

In The News

New Faculty - Spring/Summer 2016
UW School of Public Health News, 07/22/2016